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Published SPNSG Studies

A. IgA Nephropathy (IgAN) I. Nephrotic Syndrome (NS)
B. Focal Segmental Glomerulosclerosis (FSGS) J. Polycystic kidney disease (PKD)
C. Membranous GN (MGN) K. Anemia of chronic renal failure (CRF)
D. Membrano-proliferative GN Type 2 (MPGN Type 2) L. Growth failure in CRF
E. Diffuse mesangial hypercellularity (DMH) M. Vesico-ureteral reflux (VUR)
F. Crescentic Glomerulonephritis (CrGN) N. Hypercalciuria (HC)
G. Tubulo-interstitial nephrititis (TIN) O. Dialysis in children
H. Hemolytic-Uremic Syndrome (HUS) P. Diabetic Nephropathy

A.     IgA Nephropathy (IgAN)

Southwest Pediatric Nephrology Study Group: A multicenter study of IgA nephropathy in children. Kidney Int 22:643‑652, 1982.

Southwest Pediatric Nephrology Study Group: Association of IgA nephropathy with steroid‑responsive nephrotic syndrome. Am J Kidney Dis 3:157‑164, 1985.

Hogg RJ, Silva FG, Wyatt RJ, Reisch JS, Argyle JC, Savino D: Prognostic indicators in children with IgA nephropathy–A report of the Southwest Pediatric Nephrology Study Group. Pediatr Nephrol 8:15-20, 1994.

Hogg RJ for the SPNSG: A randomized, placebo-controlled, multicenter trial evaluating a) alternate day prednisone b) fish oil supplements in young patients with IgA nephropathy. Am J Kidney Dis 26:792-6, 1995.

B.     Focal Segmental Glomerulosclerosis (FSGS)

Southwest Pediatric Nephrology Study Group: Focal segmental glomerulosclerosis in children with idiopathic nephrotic syndrome. Kidney Int 27:442-449, 1985.

C.     Membranous GN (MGN)

Southwest Pediatric Nephrology Study Group: Hepatitis B surface antigenemia in North American children with membranous glomerulo­nephropathy. J Pediatr 106:571‑578, 1985.

Southwest Pediatric Nephrology Study Group: Comparison of idiopathic and systemic lupus erythematosus associated membranous glomerulonephropathy in children. Am J Kidney Dis 7:115‑124, 1986.

D.     Membrano-proliferative GN Type 2 (MPGN Type 2)

Southwest Pediatric Nephrology Study Group: Dense deposit disease in children: prognostive value of clinical and pathologic indicators. Am J Kidney Dis 6:161‑169, 1985.

E.     Diffuse mesangial hypercellularity (DMH)

Southwest Pediatric Nephrology Study Group: Childhood nephrotic syndrome associated with diffuse mesangial hypercellularity. Kidney Int 23:87‑94, 1983.

F.     Crescentic Glomerulonephritis (CrGN)

Southwest Pediatric Nephrology Study Group: A clinico‑pathologic study of crescentic glomerulonephritis in 50 children. Kidney Int 27:450‑458, 1985.

G.     Tubulo-interstitial nephrititis (TIN)

Hawkins EP, Berry PL, Silva FG for the Southwest Pediatric Nephrology Study Group: Acute tubulointerstitial nephritis in children: clinical, morphologic, and lectin studies. Am J Kidney Dis 14:466-471, 1989.

H.     Hemolytic-Uremic Syndrome (HUS)

Argyle JC, Hogg RJ, Pysher TJ, Silva FG, Siegler RL: A clinicopathologic study of 24 children with hemolytic uremic syndrome: A report of the Southwest Pediatric Nephrology Study Group. Pediatr Nephrol 4:52-58, 1990.

I.     Nephrotic Syndrome (NS)

Hogg RJ, Silva FG, Berry PH, Wenzl JE: Glomerular lesions in adolescents with gross hematuria or the nephrotic syndrome. A report of the Southwest Pediatric Nephrology Study Group. Pediatr Nephrol 7:27-31, 1993.

J.     Polycystic kidney disease (PKD)

Cole BR, Conley SB, Stapleton FB for the Southwest Pediatric Nephrology Study Group: Polycystic kidney disease in the first year of life. J Pediatr 111:693-699, 1987.

Verani R, Walker P, Silva FG for the Southwest Pediatric Nephrology Study Group: Renal cystic disease of infancy. Results of histochemical studies. Pediatr Nephrol 3:37-42, 1989.

K.     Anemia of chronic renal failure (CRF)

Beckman BS, Brookins JW, Shadduck RK, Mangan KF, Deftos LD, Fisher JW: Effect of different modes of dialysis on serum erythropoietin levels in children. A report of the Southwest Pediatric Nephrology Study Group. Pediatr Nephrol 2:436-441, 1988.

Beckman BS, Brookins J, Fisher JW: Measurement of erythropoietin in anephric children. A report of the Southwest Pediatric Nephrology Study Group. Pediatr Nephrol 3:75-79, 1989.

L.     Growth failure in CRF

Uauy R, Hogg RJ, Holliday M: Protein-energy requirements of children with chronic renal insufficiency: report from the Southwest Pediatric Nephrology Study Group and the Infant Diet Protein Study Group. Sem Nephrol 9:24-30, 1989.

Uauy RD, Hogg RJ, Brewer ED, Reisch JS, Cunningham C, Holliday MA: Dietary protein and growth in infants with chronic renal insufficiency: a report from the Southwest Pediatric Nephrology Study Group and the University of California, San Francisco. Pediatr Nephrol 8:45-50, 1994.

Powell DR, Liu F, Baker BK, Hintz RL, Durham SK, Brewer ED, Frane JW, Tonshoff B, Mehls O, Wingen A-M, Watkins SL, Lee PDK, Hogg RJ: Insulin-like growth factor binding protein-6 levels are elevated in serum of children with chronic renal failure. Report from the Southwest Pediatric Nephrology Study Group. J Clin Endocrinol Metab 82:2978-2984, 1997.

Powell DR, Liu F, Baker BK, Hintz RL, Lee PDK, Durham SK, Brewer ED, Frane JW, Watkins SK, Hogg RJ: Modulation of growth factors by growth hormone in children with chronic renal failure. A Report of the Southwest Pediatric Nephrology Study Group. Kidney Int 51:1970-1979, 1997.

Powell DR, Durham SK, Liu F, Baker BK, Lee PDK, Watkins SL, Campbell PG, Brewer ED, Hintz RL, Hogg RJ: The Insulin-Like Growth Factor Axis and Growth in Children with Chronic Renal Failure: A Report of the Southwest Pediatric Nephrology Study Group. J Clin Endocrinol Metab 83: 1654-1661, 1998.

Powell DR, Durham SK, Brewer ED, Frane JW, Watkins SL, Hogg RJ, Mohan S: Effects of Chronic Renal Failure and Growth Hormone on Serum Levels of Insulin-Like Growth Factor-Binding Protein-4 (IGFBP-4) and IGFBP-5 in Children: A Report of the Southwest Pediatric Nephrology Study Group. J Clin Endocrinol Metab 84: 596-601, 1999.

M.     Vesico-ureteral reflux (VUR)

Arant BS: Medical management of mild to moderate vesicoureteral reflux: Follow-up studies of infants and young children. A preliminary report of the Southwest Pediatric Nephrology Study Group. J Urol 148:1683-1687, 1992.

N.     Hypercalciuria (HC)

Stapleton FB: Idiopathic hypercalciuria: a prominent cause of isolated hematuria in children. A report of the Southwest Pediatric Nephrology Study Group. Kidney Int 37:807-811, 1990.

O.     Dialysis in children

Southwest Pediatric Nephrology Study Group: Continuous ambulatory and continuous cycling peritoneal dialysis in children. Kidney Int 27:558‑564, 1985.

P.     Diabetic Nephropathy

Ellis EN: Renal disease in adolescents with Type I diabetes mellitus: a report of the Southwest Pediatric Nephrology Study Group (Director: Hogg RJ). Am J Kidney Dis 22:783-790, 1993.

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